Enzymes modify solid-to-liquid interactions, therefore having more impact on the rock surface than the oil–water interface. The de-adhesion of crude oil from the rock is related to the catalytic effect of the enzymes.

Enzymes are biological catalysts that expedite reactions. Naturally, all proteins have surface activity potential.

GreenZyme®'s clearest measurable result wasn't a bigger oil rate — it was a lasting drop in water-in-oil emulsion. Crude oil polishing begins in the reservoir.